DRAGEN ORA Decompression v2.7

Warning Do not use this documentation for decompression on the DRAGEN Server. The DRAGEN Server has its own integrated DRAGEN ORA Decompression component.

DRAGEN ORA Decompression Software decompresses fastq.ora files into fastq.gz files. Fastq.ora files are generated using lossless compression technology as part of DRAGEN. Orad is the executable file that runs the DRAGEN ORA Decompression Software, which is a standalone piece of software.

With DRAGEN v4.3, compression of FASTQ files derived from supported non-human species and from human bisulfite data (methylated DNA application) is available. DRAGEN ORA decompression v2.7 allows for the decompression of FASTQ.ORA compressed with all supported references. Refer to the References Installation and Supported References sections.

The DRAGEN ORA Decompression Software is available for the following operating systems in three separated executable:

• Linux

• Mac

• Windows

Decompression of FASTQ.ORA stored on local storage is supported on Linux, Mac, and Windows. Decompression of FASTQ.ORA stored on AWS S3 is only supported on Linux.

Decompression of FASTQ.ORA stored on Azure Blob storage is only supported on Linux.

When FASTQ.ORA is located on AWS S3 or Azure Blob storage, the decompression occurs on a streaming mode: the FASTQ.ORA file does not need to be fully transferred before decompression can start.